Technical Case Studies

Date Posted

Allo-Antibody Identification Cases


ABID Technical Case 1
01/19/2009


ABID Technical Case 2
01/19/2009


ABID Technical Case 3
01/19/2009


ABID Technical Case 4
01/21/2009


ABID Technical Case 5
01/21/2009


ABID Technical Case 6
01/22/2009


ABID Technical Case 7
01/22/2009


ABID Technical Case 8
01/22/2009


ABID Technical Case 9
01/22/2009


ABID Technical Case 10
01/23/2009


ABID Technical Case 11
01/23/2009


ABID Technical Case 12
01/23/2009


ABID Technical Case 13
01/23/2009


ABID Technical Case 14
01/23/2009


ABID Technical Case 15
01/23/2009


ABID Technical Case 16
01/23/2009


ABID Technical Case 17
01/23/2009


ABID Technical Case 18
01/23/2009


ABID Technical Case 19
01/23/2009


ABID Technical Case 20
01/23/2009


ABID Technical Case 21
01/23/2009


ABID Technical Case 22
01/23/2009


ABID Technical Case 23
01/23/2009



ABO Discrepancies


ABO Discrepancy Technical Case 1
01/23/2009


ABO Discrepancy Technical Case 2
01/23/2009


ABO Discrepancy Technical Case 3
01/23/2009


ABO Discrepancy Technical Case 4
01/23/2009


ABO Discrepancy Technical Case 5
01/23/2009


ABO Discrepancy Technical Case 6
01/23/2009


ABO Discrepancy Technical Case 7
01/23/2009



Autoantibodies


Autoantibody Technical Case 1
01/23/2009


Autoantibody Technical Case 2
01/23/2009


Autoantibody Technical Case 3
01/23/2009


Autoantibody Technical Case 4
01/23/2009


Autoantibody Technical Case 5
01/23/2009


Autoantibody Technical Case 6
01/23/2009


Autoantibody Technical Case 7
01/23/2009


Autoantibody Technical Case 8
01/23/2009


Autoantibody Technical Case 9
01/23/2009


Autoantibody Technical Case 10
01/23/2009



Antibodies Causing Hemolytic Disease of the Fetus and Newborn


HDN Technical Case 1
02/15/2009


HDN Technical Case 2
02/15/2009


HDN Technical Case 3
02/15/2009


HDN Technical Case #4
06/24/2010


HDN Technical Case #5
06/24/2010



Clinical Case Studies

Date Posted

Autoimmune Hemolytic Anemia Clinical Cases


A Patient With a High Reticulocyte Count
02/12/2009


A Blood Banker’s Nightmare
02/13/2009


A 6 Month Old Girl with Hemolytic Anemia
02/13/2009


Acute Hemolytic Anemia in a 15 Year Old
02/13/2009


A New Panagglutinin in a Transfusion Dependent Patient
02/13/2009



Hemolytic Disease of the Fetus and Newborn Clinical Cases


Everything You Need to Know About HDN
02/12/2009


HDN Due to Anti-D Plus Anti-C
02/16/2009


Icterus Praecox
02/16/2009


Erythroblastosis Fetalis without an Obvious Cause
06/24/2010


Another Case of Severe HDN with a Negative Maternal Antibody Screen
06/24/2010



Transfusion Reaction Clinical Case Studies


The Worst Pain I’ve Ever Had
02/15/2009


Fatal IHTR due to an ABO Mismatch
03/23/2009


IHTR after a Negative Antibody Detection Test
03/23/2009


Fatal IHTR due to anti-Di(b)
05/06/2009


A Febrile Reaction in a Woman with Anti-Fy(a)
08/02/2009


Hemolysis after Platelet Transfusion
08/02/2009


Red Urine in a Recently Transfused Woman
08/02/2009


Hemoglobinuria in the Operating Room
08/02/2009


Fever after Directed Donor RBCs
08/02/2009


Transfusion Complicated by Shock
08/02/2009


Jaundice and Rash 24 Days after Cardiac Surgery
08/02/2009


A Transfusion-Related Respiratory Event
08/23/2009


Pulmonary Edema after Rapid Transfusion of FFP
08/23/2009



Drug-Induced Immune Hemolytic Anemia


Fatal Hemolysis 13 Days after Caeserian Section
10/05/2011


Hemolysis after Chemotherapy
10/05/2011



Sickle Cell Disease


Post-op Post-transfusion Crisis in a SCD Patient
08/02/2009



Case of the Month

Date Posted


Case of the month 7, Nov ’10
11/30/2010


Case of the Month 6, Nov ’09
11/18/2009


Case of the Month 5, Aug ’09
08/09/2009


Case of the Month 4, May ’09
05/06/2009


Case of the Month 3, Feb ’09
02/18/2009


Case of the Month 2, May ’08
02/17/2009


Case of the Month 1, April ’08
02/16/2009





ripal-and-ari-studying.jpg
V. Harimoorthy and Dr. Ripal Shah working on a case study

About Our Case Studies

Click here for a list with case summaries.

All case studies are real cases. The antibody identification panels depicted include the actual RBC phenotypes and reaction strengths as they were read by the technologists doing the work. With rare exceptions, no changes were made to make them easier or more “correct” for the student. The only editing made to some cases was omission of duplicate work and repeat testing. All cases include patient history, but the Technical Case Studies largely focus on the laboratory investigation while the Clinical Case Studies focus to a greater degree on the clinical context of the investigation.  The Case of the Month may be of either type.

Our Case of the Month is indeed a case study, but alas, it may not occur monthly.  However, we are working on it!

We suggest that the student try to answer all questions before looking at the author’s answers.  Many of the answers are based on the specific policies and procedures posted in the Procedures section of this website.  Laboratories may follow different policies and procedures than these, and such different policies might lead to different answers.  Important policies and procedures for answering the case study questions include ”Investigation of a Positive Antibody Detection Test“, “Antigen Treatment Effects“, “Blood Component Compatibility Requirements“, and “Investigation of a Positive DAT“.   Special procedures cited in the case studies are posted under the “Procedures” tab.

If you a teacher of immunohematology we invite you to use one or more case studies in your own teaching.  The case list will help you in selecting those that will be useful to the learners you’re working with.  Please note that the case studies are copyrighted and must not be attributed to other authors so leave the author’s name and copyright symbol on the case if you print it.  We are interested in disseminating this knowledge and would like to know whether and how the material is being used.  Also, we welcome your feedback, positive or negative.  So please tell us if the material is helpful, if you find any errors we need to fix, or if there is something else you want to see here.